VASCULAR BIOLOGY von Willebrand factor promotes leukocyte extravasation
نویسندگان
چکیده
1Max Planck Institute for Molecular Biomedicine, Münster, Germany; 2Institute for Surgical Research, University of Munich, Munich, Germany; 3Department of Anesthesiology and Critical Care Medicine, University of Münster, Münster, Germany; 4Department of Dermatology, University of Münster, Münster, Germany; and 5University Clinic and Rudolf Virchow Center, University of Würzburg, Würzburg, Germany.
منابع مشابه
von Willebrand factor directly interacts with DNA from neutrophil extracellular traps.
OBJECTIVE Inflammatory conditions provoke essential processes in the human vascular system. It leads to the formation of ultralarge von Willebrand factor (VWF) fibers, which are immobilized on the endothelial cell surface and transform to highly adhesive strings under shear conditions. Furthermore, leukocytes release a meshwork of DNA (neutrophil extracellular traps) during the process of the r...
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